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April 1977

Signs of Interhemispheric Disconnection in Marchiafava-Bignami Disease

Author Affiliations

From the Neuropsychology Research Group and the Department of Neurology and Neuropsychology, Hôpital de la Salpêtriére, Paris.

Arch Neurol. 1977;34(4):254. doi:10.1001/archneur.1977.00500160068015

• We report three cases of Marchiafava-Bignami disease. The diagnosis was made on clinical grounds. Evidence of interhemispheric disconnection was found in all three cases. This included left hand anomia, left-sided apraxia, left-hand agraphia, and left-sided pseudoextinction to both visual and tactile stimuli. In two cases, there was a left-ear extinction on a dichotic listening test.