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September 1977

Evoked Response and After-Discharge Thresholds to Electrical Stimulation in Temporal Lobe Epileptics

Author Affiliations

From the Departments of Neurology (Dr Walter), Neurosurgery (Ms Cherlow, Drs Dymond and Crandall), Psychiatry (Dr Serafetinides), and the Brain Research Institute (Dr Crandall), UCLA Center for the Health Sciences, and the Brent-wood Veterans Administration Hospital (Drs Serafetinides and Dymond), Los Angeles.

Arch Neurol. 1977;34(9):527-531. doi:10.1001/archneur.1977.00500210029003

• The records of electrical stimulation of 30 psychomotor epileptics were examined for threshold levels of evoked responses and after-discharge production. Comparisons were made between anatomical sites, operated and nonoperated structures, and different disease states. It was found that patients with hippocampal sclerosis (HS) had higher thresholds in structures on the operated side. The patients with lesions other than HS were found to differ from those with hippocampal sclerosis in that there were no differences found between their diseased and nondiseased structures. For both patient groups, the amygdala had a much higher threshold for after-discharge production than either the hippocampus or the hippocampal gyrus.