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Article
November 1979

Trial of Baclofen in Amyotrophic Lateral Sclerosis

Author Affiliations

From the Institutes of Medical Sciences, San Francisco (Drs Norris and U), and the Medical Department, Pharmaceutical Division, CIBA-Geigy Corp, Summit, NJ (Drs Sachais and Carey).

Arch Neurol. 1979;36(11):715-716. doi:10.1001/archneur.1979.00500470085019
Abstract

• A trial of the antispastic drug baclofen was made in amyotrophic lateral sclerosis. Some patients noted reduction of tonus and spasticity; but others had no benefit, nor was the course of the disease altered by long-term administration of baclofen. No major side effects occurred.

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