July 1980

AdrenoleukodystrophyReport of Two Cases With Relapsing and Remitting Courses

Author Affiliations

From the Department of Neuropathology, the Hospital for Sick Children, London. Dr Walsh is now with The Hospital for Sick Children, Toronto.

Arch Neurol. 1980;37(7):448-450. doi:10.1001/archneur.1980.00500560078013

• Two boys with adrenoleukodystrophy (ALD) had unusual clinical courses. The first had three episodes of relapse and two remissions associated with elevation and fall in CSF protein levels. The second boy has had a prolonged remission of his neurologic symptoms with continuing adrenocortical failure. There may be a limited role for steroids in the treatment of the cerebral aspects of ALD.