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Article
October 1983

Microorganisms as Antineoplastic Agents in CNS Tumors

Author Affiliations

From the Department of Neurosurgery, University of Mississippi Medical Center, Jackson.

Arch Neurol. 1983;40(10):637-642. doi:10.1001/archneur.1983.04050090073012
Abstract

• In two patients, malignant tumors unexpectedly regressed following infections. I reviewed the extensive body of literature, both experimental and clinical, concerning the antineoplastic potential of bacteria and viruses. Substantial evidence exists to indicate that microorganisms may, by growing in or near tumors, completely or partially inhibit tumor growth, or alternatively may have no effect at all. In fact, oncolysis may occur only when a specific organism infects a specific tumor.

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