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Article
March 1984

Multiple Sclerosis and Hypokalemic Periodic Paralysis

Author Affiliations

Department of Neurology Sheba Medical Center University of Tel Aviv Tel Hashomer, Israel

Arch Neurol. 1984;41(3):252. doi:10.1001/archneur.1984.04050150030009
Abstract

To the Editor.  —In a recent issue of the Archives, Toglia et al1 referred to an instance of the association of multiple sclerosis (MS) and hypokalemic paralysis in the same person, which they believed to be the first reported.A similar case history has, in fact, already been recorded from this department.2As in the patient described by these authors, our patient had, during a period of years, two distinct sets of symptoms. One was clinically and biochemically typical of hypokalemic periodic paralysis, and the other, entirely appropriate for the diagnosis of MS, with a number of separate events related to lesions scattered in the CNS.The question posed by Toglia and colleagues, as to whether the association of these disorders was meaningful or simply coincidental, was also raised by us. Although there are now two cases on record, it still seems a little premature to make a

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