September 1987

Comparison of Two Screening Tests in Alzheimer's DiseaseThe Correlation and Reliability of the Mini-Mental State Examination and the Modified Blessed Test

Author Affiliations

From the Center for the Study of Aging and Human Development (Dr Fillenbaum), the Division of Neurology, Department of Medicine (Dr Heyman and Ms Haynes), and the Division of Biometry, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC.

Arch Neurol. 1987;44(9):924-927. doi:10.1001/archneur.1987.00520210026014

• The Mini-Mental State Examination (MMSE) and the Blessed Orientaion-Memory-Concentration test (BOMC), a sixitem derivative of the Blessed Information-Memory-Concentration Test, were each administered to 36 patients with a clinical diagnosis of Alzheimer's disease. In 24 patients, both tests were readministered a month later. The correlation between the MMSE and BOMC was -0.83 with a test-retest correlation of 0.89 (MMSE) and 0.77 (BOMC). Factor analysis indicated that the multiple MMSE cognitive components could be explained by two factors, which together accounted for 66% of the variance. These factors are conceptually similar to the components of the BOMC, and so may explain the substantial correlation between the two tests. Since these cognitive status tests seem to be equivalent for Alzheimer patients, the briefer measure (BOMC), which offers additional advantages, may be preferred.