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This volume of edited articles is dedicated to the scientific achievements and influence on the field of neurobiology of Prof T. A. Sears, retired chair of the Sobell Department of Neurophysiology, Institute of Neurology, in London, England. The collection of articles was inspired by a symposium held in London to mark Sears' retirement. The book is divided into 4 sections: part 1, physiology and pathophysiology of nerve fibers; part 2, pain; part 3, control of central nervous system output; and part 4, development, survival, regeneration, and death. The overarching theme of the volume is, "Not only may the science then help the neurologist, but clinical observations may help illuminate the science."
This view has been the approach of Professor Sears in his scientific career and exemplified by the contributors. Major topics reviewed in clear and expert terms include ion channels and axon potential generation and spread and their involvement in
Rosenberg RN. The Neurobiology of Disease: Contributions From Neuroscience to Clinical Neurology. Arch Neurol. 1997;54(4):356. doi:10.1001/archneur.1997.00550160010007