edited by Merton Sandler, Michel Ferrari, and Sara Harnett, 323 pp, with illus, $93, New York, NY, Cambridge University Press, 1996.
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This volume records the proceedings of the Migraine Research Symposium held in Malaga, Spain, in May 1995. The participants were the leading migraine authorities in the basic sciences relevant to migraine—for the most part European. There are 22 chapters, each summarizing a body of work relevant to pathogenesis of migraine and each followed by open informal discussion with a question and answer format. Presentations are on a high level; this was a meeting of research workers, and there was no attempt to summarize background knowledge for those comparatively unfamiliar with the field. Conversely, the volume provides a superb up-to-the-minute coverage of the certainties and, more important, the uncertainties on a wide variety of subjects in pharmacology and physiology. The topics covered include the nature of receptor genes of possible importance in migraine and the possible role of nitric oxide, neurotropins, and perivascular peptides in migraine pathogenesis. There is, of
Ziegler DK. Migraine Pharmacology and Genetics. Arch Neurol. 1997;54(5):523. doi:10.1001/archneur.1997.00550170011007