Yamauchi et alArticle describe progressive atrophy of the corpus callosum in corticobasal degeneration with cognitive loss and quantitative reduction in cortical metabolism measured using cerebral metabolic rate of glucose values determined with positron emission tomography. It is an elegant extension of our biochemical understanding of this complex disorder.
A prospective controlled study of patients undergoing elective coronary artery bypass grafting was conducted with careful magnetic resonance imaging, electroencephalographic, neurologic, and neuropsychological assessments. Of 38 Finnish patients studied, along with 20 control patients, Vanninen and colleaguesArticle found increased electroencephalographic alterations and ischemic cerebral lesions by magnetic resonance imaging without significant change in neuropsychological test performance. These findings are important and need to be compared and contrasted with parallel studies appearing in the literature.
This Month in The Archives of Neurology. Arch Neurol. 1998;55(5):597-598. doi:10.1001/archneur.55.5.597