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Letters to the Editor
June 1998

Hemisphere-Specific Cognitive and Motor Changes After Unilateral Posteroventral Pallidotomy

Arch Neurol. 1998;55(6):881-883. doi:

We read with interest the findings and comments of Soukup et al1 in the August issue of the ARCHIVES.

First, contrary to the comment by Soukup and coworkers that our group did not observe improvement in motor coordination speed (as measured by the Purdue Pegboard [PP] Test), we did find improvements at 3 months postoperatively for the PP-preferred hand (P<.007, n=25), PP hand contralateral to posteroventral pallidotomy (PVP) lesion (P<.009, n=25), and trends toward significance for PP hand ipsilateral to PVP lesion (P<.06, n=25). Both significant findings also had strong effect sizes (Cohen d=0.52 for PP-preferred hand and Cohen d=0.37 for PP contralateral). Similar to the testing by Soukup et al, our neuropsychological testing was completed during the patients' optimal "on" state.

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