Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998
Illarioshkin et alArticle describe 6 families with a mutation in the GTP cyclohydrolase 1 (GCH-1) gene in a set of Russian families with dopa-responsive dystonia (DRD). Three new heterozygote point mutations in exons 1, 2, and 4 of the GCH-1 gene were identified in 3 families with autosomal dominant inheritance. The molecular genetics of DRD is continuing to unfold.
This Month in The Archives of Neurology. Arch Neurol. 1998;55(6):775. doi:10.1001/archneur.55.6.775