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April 1999

Neuro-oncology 1999

Arch Neurol. 1999;56(4):397-398. doi:10.1001/archneur.56.4.397

MALIGNANT BRAIN tumors occur in more than 40,000 individuals in the United States each year. About half are primary and the remainder are metastatic. Brain metastasis is frequent in patients due to several systemic malignancies including lung, breast, melanoma, lymphoma, and colon cancers. Brain tumors are the second most common cause of cancer-related death in people up to the age of 35 years. Present treatment modalities include surgery, radiation, and chemotherapy. Despite these therapeutic approaches studied comprehensively with numerous combined modality treatment trials during the past 20 years, patient survival is still numbered in months.1

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