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May 1999

Cryptogenic Sensory Polyneuropathy

Arch Neurol. 1999;56(5):519-520. doi:10.1001/archneur.56.5.519

IN THIS issue of the ARCHIVES, Wolfe et al1 characterize and suggest treatment for chronic cryptogenic sensory polyneuropathy (CSPN). They define CSPN as a disorder with "pain, numbness, and tingling in the distal extremities without symptoms of weakness." Other features are symmetry, evaluation over at least 3 months, a length-dependent polyneuropathy, and no identifiable cause. Wolfe and colleagues conclude that CSPN is common, that it tends to follow a benign clinical course, and that case management should emphasize treatment of neuropathic pain using pharmacotherapeutic principles.

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