The 3 editors of Inclusion-Body Myositis and Myopathies, Askanas, Serratrice, and King Engel are well-respected experts in the field of neuromuscular disorders and have made significant contributions to our understanding of sporadic inclusion body myositis (s-IBM) and the hereditary inclusion body myopathies (h-IBM). This book represents a comprehensive review of the clinical, laboratory, and histopathologic features of s-IBM and h-IBM as well as the possible pathogenic mechanisms of these disorders. This book is divided into 7 sections and 24 chapters, each written by renowned neuromuscular specialists with expertise in IBM. Section 1 is an overview of s-IBM and h-IBM. Section 2 is a historic perspective into these myopathies. Section 3 reviews the clinical, laboratory, histological, and pathogenic features of s-IBM, while section 4 reviews the features of the different h-IBMs. Section 5 is devoted to the possible pathogenic mechanisms leading to s-IBM and h-IBM. Finally, section 6 reviews published data regarding treatment, and more important, strategies for designing treatment studies in the future.
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