We appreciate Dr Morton's concern about the potential etiology of mild cognitive impairment reported in our study in the ARCHIVES.1 At a recent meeting, "Current Concepts in Mild Cognitive Impairment,"2 held in Chicago, Ill, from June 24 to 26, 1999, there was considerable discussion concerning the term mild cognitive impairment. The most common form of mild cognitive impairment likely involves a degenerative etiology and leads to Alzheimer disease. However, it was also recognized that there may be other causes of mild cognitive impairment that may improve, remain static, or lead to other neurological conditions.
Petersen RC, Kokmen E. Solvent Toxicity and Cognition Impairment—Reply. Arch Neurol. 2000;57(2):282. doi: