We wish to thank Dr Constantinescu for an interesting contribution to the association of CAD with acute infection. As mentioned by Dr Constantinescu, it is well established that infection of the head and neck by varicella-zoster virus can induce vasculitis and cause stroke. It is interesting for us to read that such varicella-zoster infection may also lead to CAD. This observation opens the possibility that virus-induced vasculitis may have caused the dissection in the 2 cases reported by Dr Constantinescu.
Grau AJ, Brandt T, Buggle F, Winter R, Hacke W. Association of Varicella-Zoster Virus With Cervical Artery Dissection in 2 Cases—Reply. Arch Neurol. 2000;57(3):427. doi: