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History of Neurology: Seminal Citation
June 2000


Arch Neurol. 2000;57(6):892-895. doi:10.1001/archneur.57.6.892

The anatomical correlates of aphasia were delineated in the 19th century, but clinical descriptions of the classical aphasic syndromes antedate this period. The oldest recorded text on aphasia reeks with modernity: it contains a practice guideline with advice to withhold treatment. On the Edwin Smith1 papyrus (Case 20) from the Pyramid Age (about 3000-2500 BC) (Figure 1) an Egyptian surgeon wrote:

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