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January 2001

A Real-Time Insight Into Disease Progression and the Role of Axonal Injury in Multiple Sclerosis

Arch Neurol. 2001;58(1):37-39. doi:10.1001/archneur.58.1.37

THE PAST FEW YEARS have brought significant progress in the field of multiple sclerosis (MS) research. New findings and insights, built upon a foundation of previous knowledge, have emerged into a preliminary understanding of many aspects of the disease. For example, genetics and susceptibility, identification of myelin antigens, inflammation, the roles of T cells and macrophages, mechanisms of demyelination, and reactive astrogliosis have all been studied. Drugs such as interferon beta and glatiramer acetate exert documented, albeit modest, effects during relapsing-remitting MS and are now widely available.

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