We appreciate Dr Brenner's interest in our work and the opportunity to respond to his letter. While we have previously reported on the prevalence of AD in Ballabgarh,1 our most recent article does not address the incidence or the prevalence of AD in the rural northern Indian community, but rather the relationship between AD and the APOE polymorphism.2 Our previous article, however, which our most recent article cites, discussed the same possibilities that Dr Brenner suggests as explanations for low prevalence.
Ganguli M, Pandav R. In reply. Arch Neurol. 2001;58(3):517. doi: