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Controversies in Neurology
April 2001

The Potential for Harm or Benefit From Inflammatory Processes in Stroke

Author Affiliations


Arch Neurol. 2001;58(4):674. doi:10.1001/archneur.58.4.674

GIVEN the prominent role of stroke as a cause of morbidity and mortality throughout the world, numerous attempts have been made to prevent, limit, and reverse its effects. In ischemic stroke, abundant effort has been placed on recognizing risk factors and the use of medications or surgical methods to retain or reestablish vascular patency, retard tissue damage, and promote recovery. In these two position papers, the involvement of inflammatory mediators in stroke is addressed. Both emphasize the need to focus on the secondary role of inflammatory processes in a disorder usually initiated by noninflammatory mechanisms.

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