History of Neurology: Seminal Citations
April 2001

Raeder Syndrome

Author Affiliations

From the Montefiore Medical Center and Albert Einstein College of Medicine, New York, NY.




Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001

Arch Neurol. 2001;58(4):661-662. doi:10.1001/archneur.58.4.661

In 1918, Raeder1 reported the relationship between "paralysis of the oculopupillary sympathetic [nerve]" and pain in the trigeminal nerve distribution implicating the paratrigeminal area of the middle fossa of the cranium. His first report in Norwegian was published again in Brain in 1924 with 4 other cases.2 Although Horner3 had described the features of involvement of the cervical sympathetic nerves in 1869, Raeder2 recognized that "The clinical syndrome of Horner may result from a lesion at any place in the course of these (sympathetic) fibers, but the completeness of the syndrome varies with the location of the lesion."

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