We appreciate Dr von Kummer's interest in our article. The presumed discrepancies, however, are easy to explain. The aims of the 2 articles were different: While the American Journal of Neuroradiology (AJNR) article1 focused mainly on the feasibility of using time-to-peak (TTP) mapping during initial and early follow-up CT scans, the ARCHIVES article2 aimed to correlate additional parameters, such as final total infarct volume (hemispheric lesion volume [HLV]) calculated from follow-up CT scans, with the severity of neurological symptoms at stroke onset (National Institutes of Health Stroke Scale [NIHSS] score) and therapeutic efficacy (nutritional vs nonnutritional reperfusion). Eight additional patients with symptoms of middle cerebral artery ischemia were included in the ARCHIVES article.
Röther J, Weiller C, Reichenbach JR, Herzau M, Kaiser WA, Jonetz-Mentzel L, Fiala A. In reply. Arch Neurol. 2001;58(5):835-837. doi: