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History of Neurology: Seminal Citations
June 2001

Charcot-Marie-Tooth Disease

Author Affiliations

From the Department of Neurology, University of Utah School of Medicine, Salt Lake City.

 

CHRISTOPHER G.GOETZMD

Arch Neurol. 2001;58(6):1014-1016. doi:10.1001/archneur.58.6.1014

In 1886, Jean-Martin Charcot and Pierre Marie1,2 and Henry Tooth3 independently described the hereditary motor and sensory neuropathy that now bears their names. Their precise clinical description provided the foundation on which later physiological and genetic understanding of hereditary neuropathies is based. This article will trace the historical development of our understanding of Charcot-Marie-Tooth disease (CMT) from its early descriptions to recent genetic discoveries.

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