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History of Neurology: Seminal Citations
August 2001

Brain Abscess

Author Affiliations

From the Departments of Medicine (Neurology) (Drs Habib and Mozaffar) and Pathology (Dr Mozaffar), The Aga Khan University, Karachi, Pakistan.



Arch Neurol. 2001;58(8):1302-1304. doi:10.1001/archneur.58.8.1302

A brain abscess is a focal suppurative process in the brain parenchyma, complicating paranasal sinusitis, otitis media, cranial trauma, or bacteremia from an extracranial focus of infection. It remains a significant health care problem in developing countries, with mortality rates of up to 21%.1 The advent of modern antibiotic agents and diagnostic imaging techniques has resulted in dramatic improvements in morbidity and mortality in brain abscess. This article will trace the evolution of concepts in the management of brain abscesses through seminal citations in the medical literature.

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