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Letters to the Editor
October 2001

Does Mild Cognitive Impairment Represent Early-Stage Alzheimer Disease?

Arch Neurol. 2001;58(10):1705-1706. doi:

I have just finished reading the fascinating results of a longitudinal study of patients with mild cognitive impairment (MCI) by Morris et al1 and have a concern regarding their conclusions. This study has immense practical implications for our growing population of elderly patients. The title "Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease" reads like a welcome fresh breath of dogma in the uncertain world of clinical neurology. The authors solidify this bold title when they open the "Comment" section with the following statement: "The main finding from this study is that individuals considered by current criteria to have only MCI in fact have very mild AD [Alzheimer disease]."

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