THE RECENTLY completed working draft sequence of the human genome is a tool for identifying genetic causes of neurological diseases and therapeutic targets for their treatment. The emerging map contains 30 000 to 35 000 protein-coding genes and more than 2 million markers to help locate disease-causing genes.1,2 These landmarks form a useful guide to navigate through vast quantities of sequence, to identify disease genes that are mutated, and to screen for therapeutic targets that might offer hope for treatments.
Puls I, Lieberman AP, Fischbeck KH. Impact of the Human Genome Sequence on Neurology and Neuroscience. Arch Neurol. 2001;58(11):1750-1751. doi:10.1001/archneur.58.11.1750