[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Letters to the Editor
November 2001

In reply

Arch Neurol. 2001;58(11):1939-1940. doi:

We thank Frisoni and Geroldi for their comments regarding the severity of cerebrovascular disease and motor dysfunction. In our study, we evaluated only infarcts with volumes less than 10 cm3. We did not quantify leukoaraiosis. The patients described by Frisoni and colleagues apparently had moderately extensive leukoaraiosis as well as lacunes, although the volume of the lacunes is not specified. Nevertheless, their subjects, similar to ours, did not differ in cognitive severity. We agree with their conclusion that concomitant subcortical cerebrovascular disease does not markedly modulate cognitive clinical features of AD.

First Page Preview View Large
First page PDF preview
First page PDF preview