West syndrome is an epileptic syndrome with a devastating clinical course. In recent years, anatomic and functional neuroimaging studies have helped to diagnose the cause of the spasms in most children, but with little progress in improving the poor developmental outcome associated with this syndrome. This article cites 4 seminal observations regarding the clinical presentation, diagnosis, and treatment of infantile spasms.
Carmant L. Infantile SpasmsWest Syndrome. Arch Neurol. 2002;59(2):317-318. doi:10.1001/archneur.59.2.317