We thank Dr Gill for the positive comments about our study. Because the Predictors study started more than 14 years ago, when cholinesterase medications were not available, only 41% of the patients used in our analyses were ever prescribed these medications. In models such as those used in our report, we detected no significant association between use of cholinesterase inhibitors and any of the 4 outcomes (but there was a trend toward a protective effect for mortality).
Scarmeas N, Stern Y. Delusions and Hallucinations in Alzheimer Disease—Reply. Arch Neurol. 2006;63(4):627. doi:10.1001/archneur.63.4.627-b