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June 2006

Interleukin 4 and Interleukin 10 in Creutzfeldt-Jakob Disease

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Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2006

Arch Neurol. 2006;63(6):911. doi:10.1001/archneur.63.6.911-a

We read with great interest the recent excellent article concerning interleukin (IL) 4 and IL-10 in the cerebrospinal fluid (CSF) of patients with Creutzfeldt-Jakob disease by Stoeck et al.1 They reported that patients with Creutzfeldt-Jakob disease had elevated levels of CSF IL-4 and IL-10. They also determined that CSF IL-4 and IL-10 levels had increased in other patients with dementia compared with controls. We want to inquire about several points in their excellent study, especially on the data for patients with Creutzfeldt-Jakob disease.

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