September 2006

Interhemispheric Dissociation of Language Regions in a Healthy Subject

Author Affiliations

Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2006

Arch Neurol. 2006;63(9):1344-1346. doi:10.1001/archneur.63.9.1344

The brain is typically organized in such a way that interhemispheric transfer is reduced in favor of intrahemispheric communication.1 Functions such as language that require extensive forward and backward interactions therefore tend to be processed in 1 hemisphere. Herein, we report functional imaging data of a healthy man who showed a rare form of atypical language dominance with an interhemispheric dissociation of anterior (Broca area) and posterior (Wernicke area) language regions (“crossed language dominance”).