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Correspondence
October 2006

Nonstroke Treatment—Reply

Arch Neurol. 2006;63(10):1506-1507. doi:10.1001/archneur.63.10.1506-b

In reply

Hippocrates urged us, first, do no harm, but this should not be overinterpreted to accept no risks in making treatment decisions. Such a stance would leave us paralyzed as physicians because nearly every medical therapy and surgical intervention has a risk of complications. It is the calculus of the risk-benefit ratio that must be considered in making treatment decisions, and there has been a common misunderstanding of the math relevant to using tPA for stroke.

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