The study “Brain Abnormalities in Neuromyelitis Optica” by Pittock et al1 attracted our attention because of its important description of the existence of brain involvement in neuromyelitis optica (NMO). Taking into account those observations and the ensuing revision of diagnosis criteria for NMO, we recently reported2 the first Portuguese clinical case of NMO with positive results for serological NMO-IgG and abnormal brain magnetic resonance image (MRI) findings.
Guimarães J, Sá MJ. Devic Disease With Abnormal Brain Magnetic Resonance Image Findings: The First Portuguese Case. Arch Neurol. 2007;64(2):290-291. doi:10.1001/archneur.64.2.290