A 51-year-old man presented with a chief complaint of pain involving his dominant left hand. Over a 6-week period he had experienced the abrupt onset of progressive pain and numbness involving the sensory distribution of the median nerve. The fingers had become weak and stiff, thus causing difficulty with all motor activities. Before this, he had experienced none of the “classic” symptoms of carpal tunnel syndrome. He had, however, noted the appearance and persistence of unusual skin changes on the hand.
Nettrour JF, Eggers SD, Pittelkow MR, Matteson EL. Acute Carpal Tunnel Syndrome Preceded by 5 Years of Unusual Skin Changes. Arch Neurol. 2007;64(3):447. doi:10.1001/archneur.64.3.447