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May 2007

Stroke Caused by Human Immunodeficiency Virus–Associated Vasculopathy?—Reply

Arch Neurol. 2007;64(5):763. doi:10.1001/archneur.64.5.763-b

In reply

Vasculopathy similar to that seen in our patient has been reported in an HIV-infected neonate with herpes simplex encephalitis.1 Likewise, cytomegalovirus involvement of cerebral vessels leading to infarction has been described.2 This report by Kieburtz and colleagues2 also described HIV-associated primary central nervous system lymphoma invading cerebral blood vessel walls with resultant infarction. Primary central nervous system lymphomas in HIV are associated with Epstein-Barr virus in up to 100% of cases.3

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