Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2007
In the current “Controversies in Neurology” series, the contentious issue arises as to whether we have sufficient evidence to designate neuromyelitis optica (NMO) (Devic disease) as a disease entity distinct from multiple sclerosis (MS).1,2 As with many such debates, there will be “lumpers” (similar disorders should be characterized under a common rubric) and “splitters” (similarly appearing disorders should be differentiated on a pathophysiologic, genetic, or phenotypic basis).
Frohman EM, Kerr D. Is Neuromyelitis Optica Distinct From Multiple Sclerosis?Something for “Lumpers” and “Splitters”. Arch Neurol. 2007;64(6):903-905. doi:10.1001/archneur.64.6.903