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Controversies in Neurology
July 2008

Anticoagulation in Cerebral Venous Sinus ThrombosisAre We Treating Ourselves?

Author Affiliations

Author Affiliations: Department of Neurology, The Aga Khan University, Karachi, Pakistan.



Arch Neurol. 2008;65(7):985-987. doi:10.1001/archneur.65.7.985

There are a lot of things we know for a fact that simply aren't so. —Kevin J. McGowan

Cerebral venous sinus thrombosis (CVST) is known for its diverse clinical manifestations and unpredictable outcome. Early autopsy data suggest that it is uniformly fatal. However, the International Study on Cerebral Vein and Dural Sinus Thrombosis data show that 8% of patients with CVST died, mainly due to transtentorial herniation, unilateral focal mass effect, or diffuse edema and multiple parenchymal lesions.1

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