[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Images in Neurology
October 2009

Stroke Incidentally Identified Using Improved Positron Emission Tomography for Microglial Activation

Arch Neurol. 2009;66(10):1288-1289. doi:10.1001/archneurol.2009.208

A 42-year-old man enrolled in a research study to measure microglial activation using [O-methyl-11C] N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine ([11C]PBR28), an improved positron emission tomography (PET) radioligand. His history included human immunodeficiency virus infection, diabetes, hypertension, hypercholesterolemia, smoking (12 pack-years), and remote use of cocaine and heroin. Medical and neurological examination results were normal except for elevated blood pressure of 157/100 mm Hg. Brain magnetic resonance imaging (MRI) showed occasional foci of mild chronic white matter ischemia but was otherwise unremarkable (Figure, A).

First Page Preview View Large
First page PDF preview
First page PDF preview