We appreciate Dr Jaffe's thoughts on translational medicine being simply a term describing an attempt to systematize a practice that has been evolving for generations. However, the purpose of our article was less to systematize than to address how the provision of health care is changing and how all stakeholders need to be engaged to make informed decisions. These decisions involve not only which treatment options are available but how to study and identify the best treatment for individuals who do not fit demographic criteria for the implementation of treatment identified as efficacious by “gold standard” randomized controlled trials. Furthermore, we attempt to outline strategies through which access to quality health care can be realized and sustained.
Helmers SL, Phillips VL, Esper GJ. Translational Neurology—Reply. Arch Neurol. 2011;68(4):541-542. doi:10.1001/archneurol.2011.66