Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2011
Intravenous thrombolysis in an extended time window has been proposed in anterior circulation stroke based on the presence of a mismatch between the diffusion and perfusion lesions on magnetic resonance imaging (MRI).1 A single report discussed this strategy in patients presenting beyond 4.5 hours with a minor posterior circulation stroke.2 We describe a patient with vertebrobasilar stroke treated 6 hours after symptom onset, using the diffusion-perfusion mismatch paradigm.
Gobert F, Cho T, Desilles JP, Hermier M, Mechtouff L, Derex L, Nighoghossian N. Magnetic Resonance Imaging–Based Intravenous Thrombolysis 6 Hours After Onset of Minor Cerebellar Stroke. Arch Neurol. 2011;68(5):678. doi:10.1001/archneurol.2011.87