This Viewpoint discusses recent advances in the understanding of seizure disorders and future pathways of discovery for the treatment of epilepsy.
This Viewpoint discusses where dementia research dementia research should be in 10 years and what we need to do to get there.
This case-control study assesses an algorithm for diagnosis of Creutzfeldt-Jakob disease using cerebrospinal fluid and olfactory mucosa samples among patients with possible, probable, or suspected disease.
This study uses cerebrospinal fluid samples from patients with Parkinson disease to develop an assay for diagnosis of Parkinson disease.
This population-based cohort study assesses the risk for intracranial hemorrhage associated with the use of selective serotonin reuptake inhibitors among new users of antidepressants and according to the strength of inhibition of serotonin reuptake.
This cohort study analyzes the association between periodic and rhythmic pattern frequency and increased risk for seizures in critically ill patients.
This cohort study assesses the association between serum albumin levels and the clinical course and outcome of Guillain-Barré syndrome in patients treated with intravenous immunoglobulin.
This randomized clinical trial assesses the efficacy and safety of opicapone as adjunct to levodopa therapy in patients with Parkinson disease experiencing end-of-dose motor fluctuations.
This study examines the associations between β-amyloid kinetics, age, amyloid, and the β-amyloid day/night pattern in older adults.
This randomized clinical trial investigates the efficacy and safety of safinamide (an oral aminoamide derivative with dopaminergic and nondopaminergic actions) as compared with placebo in levodopa-treated patients with motor fluctuations.
This study analyzes the association between exposure to statins and Alzheimer disease risk among Medicare beneficiaries.
This narrative review provides an overview of options for adapting treatment for patients with Parkinson disease who fast during Ramadan.
This case report describes a 26-year-old man with mild cerebellar and noticeable thoracic spinal cord atrophy.
This case report describes a man in his 60s with impaired level of alertness, convulsive-like movements of the limbs, and vertical nystagmus.
A 51-year-old man presented with progressive difficulty walking and deciphering speech. One month later, he required a wheelchair, declined cognitively, and developed personality changes and seizures, eventually becoming completely mute. What is your diagnosis?
A 21-year-old woman presented with a 3-year history of progressive depression, bradyphrenia, dyscalculia, and fatigue, necessitating withdrawal from college. What is your diagnosis?