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June 2017 - July 1959

Decade

Year

Issue

July 2017, Vol 74, No. 7, Pages 755-873

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2017;74(7):755. doi:10.1001/jamaneurol.2016.4004
Viewpoint

Dementia Care, Women's Health, and Gender EquityThe Value of Well-Timed Caregiver Support

Abstract Full Text
JAMA Neurol. 2017;74(7):757-758. doi:10.1001/jamaneurol.2017.0403

This Viewpoint discusses gender inequity among caregiving for individuals with dementia and its effects on women’s health.

Integrating Models of Neurologic and Psychiatric Disease

Abstract Full Text
JAMA Neurol. 2017;74(7):759-760. doi:10.1001/jamaneurol.2017.0309

This Viewpoint discusses the interface between neurology and psychiatry to address nervous system disorders.

Editorial

Lack of Evidence for Benefit From Long-term Use of Opioid Analgesics for Patients With Neuropathy

Abstract Full Text
JAMA Neurol. 2017;74(7):761-762. doi:10.1001/jamaneurol.2017.0466

Functional Decline 5 Years After Blast Traumatic Brain InjurySounding the Alarm for a Wave of Disability?

Abstract Full Text
JAMA Neurol. 2017;74(7):763-764. doi:10.1001/jamaneurol.2017.0176

Implementation of Rapid Treatment and Interfacility Transport for Patients With Suspected Stroke by Large-Vessel OcclusionIn One Door and Out the Other

Abstract Full Text
JAMA Neurol. 2017;74(7):765-766. doi:10.1001/jamaneurol.2017.0324

Linking Amyloid-β and Tau Deposition in Alzheimer Disease

Abstract Full Text
JAMA Neurol. 2017;74(7):766-768. doi:10.1001/jamaneurol.2017.0323

Parkinson Disease and Autoimmune Disorders—What Can We Learn From Genome-wide Pleiotropy?

Abstract Full Text
JAMA Neurol. 2017;74(7):769-770. doi:10.1001/jamaneurol.2017.0843
Original Investigation

Association of Long-term Opioid Therapy With Functional Status, Adverse Outcomes, and Mortality Among Patients With Polyneuropathy

Abstract Full Text
has active quiz
JAMA Neurol. 2017;74(7):773-779. doi:10.1001/jamaneurol.2017.0486

This population-based cohort study quantifies the prevalence of long-term opioid use among patients with polyneuropathy and assesses the association of long-term opioid use with functional status, adverse outcomes, and mortality.

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases

Abstract Full Text
JAMA Neurol. 2017;74(7):780-792. doi:10.1001/jamaneurol.2017.0469

This study of combination of genome-wide association data with case-control replication tests the hypothesis that there are common genetic risk variants conveying risk of both Parkinson disease and autoimmune diseases (ie, pleiotropy) and identifies new shared genetic variants and their pathways by applying a novel statistical framework in a genome-wide approach.

Association of a Primary Stroke Center Protocol for Suspected Stroke by Large-Vessel Occlusion With Efficiency of Care and Patient Outcomes

Abstract Full Text
JAMA Neurol. 2017;74(7):793-800. doi:10.1001/jamaneurol.2017.0477

This cohort study reports on the association of a primary stroke center protocol with the efficiency of care and the outcomes of patients with suspected emergent large-vessel occlusion who first present to a primary stroke center.

Population-Based Prevalence of Cerebral Cavernous Malformations in Older AdultsMayo Clinic Study of Aging

Abstract Full Text
JAMA Neurol. 2017;74(7):801-805. doi:10.1001/jamaneurol.2017.0439

This population-based study analyzes the magnetic resonance imaging brain scans of participants in the Mayo Clinic Study of Aging to determine the prevalence of cerebral cavernous malformation in adults aged 50 to 89 years.

Complex and Dynamic Chromosomal Rearrangements in a Family With Seemingly Non-Mendelian Inheritance of Dopa-Responsive Dystonia

Abstract Full Text
JAMA Neurol. 2017;74(7):806-812. doi:10.1001/jamaneurol.2017.0666

This case series elucidates the causal genetic variant in a large US family with co-occurrence of dopa-responsive dystonia as well as skeletal and eye abnormalities (ie, ptosis, myopia, and retina detachment).

Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex

Abstract Full Text
JAMA Neurol. 2017;74(7):813-820. doi:10.1001/jamaneurol.2017.0263

This cross-sectional study examines the spatial distributions of tau and Aβ deposits in the brains of elderly, cognitively normal individuals.

Early Clinical Predictors of 5-Year Outcome After Concussive Blast Traumatic Brain Injury

Abstract Full Text
has active quiz
JAMA Neurol. 2017;74(7):821-829. doi:10.1001/jamaneurol.2017.0143

This longitudinal case-control study examines 5-year clinical outcomes among active duty military personnel with concussive blast traumatic brain injuries.

Association of Longitudinal Cognitive Decline With Amyloid Burden in Middle-aged and Older AdultsEvidence for a Dose-Response Relationship

Abstract Full Text
open access
JAMA Neurol. 2017;74(7):830-838. doi:10.1001/jamaneurol.2017.0892

This longitudinal cohort study explores how the magnitude of baseline amyloid burden predicts the rate of cognitive decline over 4 years in cognitively normal adults while controlling for dichotomized amyloid status.

Survival and Causes of Death Among People With Clinically Diagnosed Synucleinopathies With ParkinsonismA Population-Based Study

Abstract Full Text
JAMA Neurol. 2017;74(7):839-846. doi:10.1001/jamaneurol.2017.0603

This population-based study compares patients with synucleinopathies with sex- and age-matched participants without parkinsonism to determine the risk of death for each type of synucleinopathy, the median time from diagnosis to death, and the causes of death.

Association of Retinal Architecture, Intrathecal Immunity, and Clinical Course in Multiple Sclerosis

Abstract Full Text
JAMA Neurol. 2017;74(7):847-856. doi:10.1001/jamaneurol.2017.0377

This cohort study assesses whether retinal layer volumes correlate with immune cell subsets and immunoglobulin indices in cerebrospinal fluid and are associated with disease activity in patients with relapsing-remitting multiple sclerosis.

Association of Dual-Task Gait With Incident Dementia in Mild Cognitive ImpairmentResults From the Gait and Brain Study

Abstract Full Text
JAMA Neurol. 2017;74(7):857-865. doi:10.1001/jamaneurol.2017.0643

This cohort study determines whether a dual-task gait test is associated with incident dementia in mild cognitive impairment.

Images in Neurology

A Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Mimics on Brain Magnetic Resonance Imaging in Myotonic Dystrophy Type I

Abstract Full Text
JAMA Neurol. 2017;74(7):866-867. doi:10.1001/jamaneurol.2017.0399

A woman in her 50s was referred to genetic consultation owing to mitochondrial myopathy or cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy suspicion based on brain magnetic resonance imaging and was diagnosed as having myotonic dystrophy type 1.

Comment & Response

Ascertainment Bias in Statin Use and Alzheimer Disease Incidence

Abstract Full Text
JAMA Neurol. 2017;74(7):868. doi:10.1001/jamaneurol.2017.0427

Considering Spastic Paraplegia Type 7 and Adult-Onset Alexander Disease

Abstract Full Text
JAMA Neurol. 2017;74(7):868-869. doi:10.1001/jamaneurol.2017.0430

Considering Spastic Paraplegia Type 7 and Adult-Onset Alexander Disease—Reply

Abstract Full Text
JAMA Neurol. 2017;74(7):869. doi:10.1001/jamaneurol.2017.0433

Incorrect Scaling Factor and Errors in Figures and P Value Thresholds

Abstract Full Text
JAMA Neurol. 2017;74(7):869-870. doi:10.1001/jamaneurol.2017.0509

Inappropriate Comparator Group in Study of Selective Serotonin Reuptake Inhibitors and Risk for Intracranial Hemorrhage

Abstract Full Text
JAMA Neurol. 2017;74(7):870. doi:10.1001/jamaneurol.2017.0538

Inappropriate Comparator Group in Study of Selective Serotonin Reuptake Inhibitors and Risk for Intracranial Hemorrhage—Reply

Abstract Full Text
JAMA Neurol. 2017;74(7):870-871. doi:10.1001/jamaneurol.2017.0541

Could Albumin Be a Biomarker to Monitor the Effect of Intravenous Immunoglobulin on Guillain-Barré Syndrome?

Abstract Full Text
JAMA Neurol. 2017;74(7):871-872. doi:10.1001/jamaneurol.2017.0563

Could Albumin be a Biomarker to Monitor the Effect of Intravenous Immunoglobulin on Guillain-Barré Syndrome?—Reply

Abstract Full Text
JAMA Neurol. 2017;74(7):872. doi:10.1001/jamaneurol.2017.0566

Concerns Regarding Opicapone as Adjunct to Levodopa Therapy

Abstract Full Text
JAMA Neurol. 2017;74(7):872-873. doi:10.1001/jamaneurol.2017.0723

Concerns Regarding Opicapone as Adjunct to Levodopa Therapy–Reply

Abstract Full Text
JAMA Neurol. 2017;74(7):873. doi:10.1001/jamaneurol.2017.0726
Correction

Incorrect Scaling Factor and Errors in Figures and P Value Thresholds

Abstract Full Text
free access
JAMA Neurol. 2017;74(7):873. doi:10.1001/jamaneurol.2017.0586

Incorrect Conflicts of Interest Disclosures

Abstract Full Text
free access
JAMA Neurol. 2017;74(7):873. doi:10.1001/jamaneurol.2017.1153
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2017;74(7):756. doi:10.1001/jamaneurol.2016.4005
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