[Skip to Content]
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
[Skip to Content Landing]

August 2017 - July 1959

Decade

Year

Issue

June 2014, Vol 71, No. 6, Pages 665-803

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):665. doi:10.1001/jamaneurol.2013.4151
Viewpoint

The Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative and Neurology

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):675-676. doi:10.1001/jamaneurol.2014.411
Editorial

Tau as a Biomarker of Concussion

Abstract Full Text
JAMA Neurol. 2014;71(6):677-678. doi:10.1001/jamaneurol.2014.443

Idiopathic Intracranial HypertensionImportant Questions Answered With More to Come

Abstract Full Text
JAMA Neurol. 2014;71(6):678-680. doi:10.1001/jamaneurol.2014.444

The Reliability of Intraoperative Electrocorticography in Magnetic Resonance Imaging–Negative Temporal Lobe EpilepsySpikes Mark the Spot

Abstract Full Text
JAMA Neurol. 2014;71(6):681-682. doi:10.1001/jamaneurol.2014.584
Original Investigation

Blood Biomarkers for Brain Injury in Concussed Professional Ice Hockey Players

Abstract Full Text
free access has expired quiz
JAMA Neurol. 2014;71(6):684-692. doi:10.1001/jamaneurol.2014.367

Shahim et al determine whether sports-related concussion is associated with elevated levels of blood biochemical markers of injury to the central nervous system and assess whether plasma levels of these biomarkers predict return to play in professional ice hockey players with sports-related concussion. Gatson and Diaz-Arrastia provide commentary in a related editorial.

The Idiopathic Intracranial Hypertension Treatment TrialClinical Profile at Baseline

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):693-701. doi:10.1001/jamaneurol.2014.133

Wall and colleagues reported the baseline clinical and laboratory features of patients enrolled in the Idiopathic Intracranial Hypertension Treatment Trial. Volpe provided a related Article .

Interictal Scalp Electroencephalography and Intraoperative Electrocorticography in Magnetic Resonance Imaging–Negative Temporal Lobe Epilepsy Surgery

Abstract Full Text
free access has expired quiz
JAMA Neurol. 2014;71(6):702-709. doi:10.1001/jamaneurol.2014.585

Burkholder and colleagues determine whether the following are associated with surgical outcomes in patients with magnetic resonance imaging-negative temporal lobe epilepsy who underwent standard anterior temporal lobectomy: (1) unilateral-only interictal epileptiform discharges on preoperative scalp electroencephalogram; (2) complete resection of tissue generating interictal epileptiform discharges on electrocorticography; (3) complete resection of opioid-induced interictal epileptiform discharges recorded on electrocorticography; and (4) location of interictal epileptiform discharges recorded on electrocorticography.

Measuring Disease Progression in Early Parkinson DiseaseThe National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) Experience

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):710-716. doi:10.1001/jamaneurol.2014.391

In an inception cohort analysis of data from 413 patients with early, untreated Parkinson disease who were enrolled in 2 multicenter, randomized, double-blind clinical trials, Parashos and coauthors examine the value of measures of impairment, disability, and quality of life in assessing progression in early Parkinson disease.

Abnormal Neurons in Teratomas in NMDAR Encephalitis

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):717-724. doi:10.1001/jamaneurol.2014.488

To characterize the organization of neuroglial elements within ovarian teratomas resected from patients with NMDAR encephalitis, Day et al performed a case-control study. Outcome measures were atypical CNS neuronal elements in ovarian teratomas resected from cases vs controls and the relationship between atypical neurons and immune infiltrates.

Emerging β-Amyloid Pathology and Accelerated Cortical Atrophy

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):725-734. doi:10.1001/jamaneurol.2014.446

Mattsson et al test the hypothesis that the development of Aβ pathology is related to increased regional atrophy in the brains of cognitively normal (CN) persons. They studied 47 CN control subjects and 15 patients with AD dementia. The main outcome measures were group effects on regional gray matter volumes at baseline and over time.

Swiss Cheese StriatumClinical Implications

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):735-741. doi:10.1001/jamaneurol.2014.286

In a blinded, retrospective case-control study using medical records from 2000 to 2007 obtained from an magnetic resonance imaging (MRI) database at the Mayo Clinic in Rochester, Minnesota, Burnett and coauthors determine the clinical features associated with Swiss cheese striatum detected on MRI scans.

Cross-Sectional and Longitudinal Relationships Between Cerebrospinal Fluid Biomarkers and Cognitive Function in People Without Cognitive Impairment From Across the Adult Life Span

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):742-751. doi:10.1001/jamaneurol.2014.445

Li et al examine biomarkers indicative of age-related cognitive decline among older individuals with normal cognition in a cross-sectional and longitudinal study.

Comparison of Parkinson Risk in Ashkenazi Jewish Patients With Gaucher Disease and GBA Heterozygotes

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):752-757. doi:10.1001/jamaneurol.2014.313

Alcalay and colleagues estimate the age-specific risk of PD in Ashkenazi Jewish patients with type 1 GD and in GBA heterozygotes.

Correlation of Parkinson Disease Severity and 18F-DTBZ Positron Emission Tomography

Abstract Full Text
free access has multimedia
JAMA Neurol. 2014;71(6):758-766. doi:10.1001/jamaneurol.2014.290

Hsiao and colleagues used [18F]9-fluoropropyl-(+)-dihydrotetrabenazine (18F-DTBZ) positron emission tomography to explore the characteristics of vesicular monoamine transporter type 2 imaging in patients with Parkinson disease (PD) with different severity levels as well as to investigate its capability in monitoring clinical severity.

Case Report/Case Series

Central Nervous System Manifestation of IgG4-Related Disease

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):767-770. doi:10.1001/jamaneurol.2014.40

Regev and coauthors described a patient with multiorgan IgG4-related disease who developed progressive spastic hemiparesis and dementia.

Multiple System Atrophy and Amyotrophic Lateral Sclerosis in a Family With Hexanucleotide Repeat Expansions in C9orf72

Abstract Full Text
free access has multimedia
JAMA Neurol. 2014;71(6):771-774. doi:10.1001/jamaneurol.2013.5762

Goldman and colleagues described a 65-year-old woman had a 2-year history of ataxia with autonomic dysfunction, but without motor neuron signs, who was diagnosed as having multiple system atrophy (MSA) based on her clinical history and the hot cross bun sign on brain magnetic resonance imaging.

Expanded C9ORF72 Hexanucleotide Repeat in Depressive Pseudodementia

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):775-781. doi:10.1001/jamaneurol.2013.6368

Bieniek and coauthors assess the incidence of the expanded C9ORF72 repeat in cases of depressive Pseudodementia.

Infantile Spasms and Hyperekplexia Associated With Isolated Sulfite Oxidase Deficiency

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):782-784. doi:10.1001/jamaneurol.2013.5083

Holder et al describe an infant who had the characteristic presentation of isolated sulfite oxidase deficiency but, in addition to seizures, developed infantile spasms and hyperekplexia.

Review

IgG4-Related Hypertrophic PachymeningitisClinical Features, Diagnostic Criteria, and Treatment

Abstract Full Text
JAMA Neurol. 2014;71(6):785-793. doi:10.1001/jamaneurol.2014.243

Lu and colleagues summarize the current knowledge on IgG4-RHP including its pathological, clinical, and radiological presentations. Particular emphasis is placed on diagnostic and therapeutic implications.

Clinical Pathologic Conference

Progressive Neuropsychiatric Symptoms and Motor Impairment

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):794-798. doi:10.1001/jamaneurol.2013.6308

Ghadiri and coauthors report of a case in which a 42-year-old white man presented with cognitive impairment and behavioral changes followed by rapidly progressive motor and gait impairment. Magnetic resonance imaging revealed striking multifocal white matter signal change, areas of restricted diffusion, diffuse callosal signal change, and atrophy and hyperintensity of the corticospinal tracts.

Comment & Response

Methylation Analysis in Newborn Screening for Fragile X Syndrome

Abstract Full Text
JAMA Neurol. 2014;71(6):800. doi:10.1001/jamaneurol.2014.142

Methylation Analysis in Newborn Screening for Fragile X Syndrome—Reply

Abstract Full Text
JAMA Neurol. 2014;71(6):800-801. doi:10.1001/jamaneurol.2014.454

Medulloblastoma and Dizziness

Abstract Full Text
JAMA Neurol. 2014;71(6):801. doi:10.1001/jamaneurol.2014.173

Medulloblastoma and Dizziness—Reply

Abstract Full Text
JAMA Neurol. 2014;71(6):801-802. doi:10.1001/jamaneurol.2014.522

Intrathecal Gadolinium for Magnetic Resonance Myelography in Spontaneous Intracranial Hypotension: Valuable But May Be Risky

Abstract Full Text
JAMA Neurol. 2014;71(6):802. doi:10.1001/jamaneurol.2014.224

Intrathecal Gadolinium for Magnetic Resonance Myelography in Spontaneous Intracranial Hypotension: Valuable But May Be Risky—Reply

Abstract Full Text
JAMA Neurol. 2014;71(6):802-803. doi:10.1001/jamaneurol.2014.577
Correction

Incorrect Value in Table

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):803. doi:10.1001/jamaneurol.2014.1265

Incorrect Information in Abstract

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):803. doi:10.1001/jamaneurol.2014.1559
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2014;71(6):671. doi:10.1001/jamaneurol.2013.4152
×