This Viewpoint discusses 2 next-generation approaches to diagnosis and therapy that are either already clinically relevant or likely to be tested in central nervous system neurotropic viral infections in the near future.
This case series describes the prenatal evolution and perinatal outcomes of 11 neonates who had developmental abnormalities and neurological damage associated with maternal Zika virus infection in Brazil.
This multicenter cohort study examines the use of florbetapir F 18 positron emission tomography in the confirmation or change in the diagnosis of Alzheimer disease and other cognitive impairment disorders.
This cross-sectional study evaluates the associations between nutrients, individually and in groups, and amyotrophic lateral sclerosis function and respiratory function at diagnosis.
This case series describes the features of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia and performs genetic sequencing in patients who do not carry CSF1R mutations.
This analysis of data collected from consecutive patients admitted with primary lobar or deep intracerebral hemorrhage to a single tertiary care medical center investigates the association between key magnetic resonance imaging markers of small vessel disease and hematoma volume and expansion.
This cross-sectional study assesses the prevalence of GBA gene mutations in Ashkenazi Jews with clinically probable or possible dementia with Lewy bodies, and associations between GBA carrier status and disease severity.
This cross-sectional study assesses the feasibility of sporadic Creutzfeldt-Jakob disease diagnosis by adaptation of an established variant Creutzfeldt-Jakob disease diagnostic blood test to urine.
This population-based cohort study uses data from the New York State SPARCS database to examine the risk of stroke in women of childbearing age who are pregnant or post partum compared with the risk in those who are not pregnant.
This cross-sectional study examines the prevalence of polyneuropathy stratified by glycemic status in obese and lean participants and investigates the association of specific components of metabolic syndrome with polyneuropathy.
This case-control study investigates the subregional pattern of striatal dopamine transporter loss in patients with pure akinesia with gait freezing in comparison with patients with progressive supranuclear palsy and those with Parkinson disease.
This review uses the example of hereditary ataxias to assess the contribution of next-generation sequencing to identification of the genetic basis of neurogenetic syndromes.
A woman in her 30s with intellectual disability, primary amenorrhoea, and focal seizures described 2 years of progressive difficulties.
This case report describes the treatment of carotid intramural thrombus with intravenous tissue plasminogen activator.
A man had weakness in the distal right hand and leg; and sudden, severe neck pain that progressed to neck stiffness and shoulder pain; magnetic resonance imaging revealed abnormal signals throughout the brain and a lesion at the level of the fifth cervical vertebra. What is your diagnosis?