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January 2017 - July 1959

Decade

Year

Issue

July 1, 2016, Vol 73, No. 7, Pages 771-896

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2016;73(7):771. doi:10.1001/jamaneurol.2015.2467
Viewpoint

Precision Medicine for Ischemic Stroke

Abstract Full Text
JAMA Neurol. 2016;73(7):773-774. doi:10.1001/jamaneurol.2016.0087

This Viewpoint discusses the future of precision medicine in the field of ischemic stroke, first looking at the current status of genetic approaches and then exploring the status of phenotype-based delineations.

Editorial

Rebound Relapses After Ceasing Another Disease-Modifying Treatment in Patients With Multiple SclerosisAre There Lessons to Be Learned?

Abstract Full Text
JAMA Neurol. 2016;73(7):775-776. doi:10.1001/jamaneurol.2016.0934

Linking Genotype to Clinical Phenotype in Multiple SclerosisIn Search of the Holy Grail

Abstract Full Text
JAMA Neurol. 2016;73(7):777-778. doi:10.1001/jamaneurol.2016.1227

The Role of Environmental Toxins in Amyotrophic Lateral Sclerosis Risk

Abstract Full Text
JAMA Neurol. 2016;73(7):779-780. doi:10.1001/jamaneurol.2016.1038

Variability in Amyotrophic Lateral Sclerosis

Abstract Full Text
JAMA Neurol. 2016;73(7):781-782. doi:10.1001/jamaneurol.2016.0729

The Age Factor in the Treatment of Glioblastoma

Abstract Full Text
JAMA Neurol. 2016;73(7):783-784. doi:10.1001/jamaneurol.2016.1331

Back to Basics—Vital Sign and Blood Glucose Abnormalities and Outcome in Childhood Arterial Ischemic Stroke

Abstract Full Text
JAMA Neurol. 2016;73(7):785-786. doi:10.1001/jamaneurol.2016.1054

Genetic Gradients in Epileptic Brain Malformations

Abstract Full Text
JAMA Neurol. 2016;73(7):787. doi:10.1001/jamaneurol.2016.1039

Pathological Diagnosis During Life in Patients With Primary Progressive AphasiaSeeking the Holy Grail

Abstract Full Text
JAMA Neurol. 2016;73(7):788-789. doi:10.1001/jamaneurol.2016.0792
Original Investigation

Rebound Syndrome in Patients With Multiple Sclerosis After Cessation of Fingolimod Treatment

Abstract Full Text
has active quiz
JAMA Neurol. 2016;73(7):790-794. doi:10.1001/jamaneurol.2016.0826

This case series describes rebound syndrome in patients with multiple sclerosis after cessation of fingolimod treatment.

Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis

Abstract Full Text
JAMA Neurol. 2016;73(7):795-802. doi:10.1001/jamaneurol.2016.0980

This case-control study examines associations between cumulative HLA genetic risk burden and clinical and MRI-based phenotypes in patients with multiple sclerosis.

Association of Environmental Toxins With Amyotrophic Lateral Sclerosis

Abstract Full Text
free access
JAMA Neurol. 2016;73(7):803-811. doi:10.1001/jamaneurol.2016.0594

This case-control study evaluates the association of exposures to environmental toxins with the odds of developing amyotrophic lateral sclerosis.

Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

Abstract Full Text
JAMA Neurol. 2016;73(7):812-820. doi:10.1001/jamaneurol.2016.1114

This genome-wide association study investigates genetic loci associated with survival in an international population of patients with amytrophic lateral sclerosis.

Combined-Modality Therapy With Radiation and Chemotherapy for Elderly Patients With Glioblastoma in the Temozolomide EraA National Cancer Database Analysis

Abstract Full Text
JAMA Neurol. 2016;73(7):821-828. doi:10.1001/jamaneurol.2016.0839

This cohort study examines data on elderly patients with glioblastoma from the National Cancer Database to compare the association of overall survival with combined-modality therapy including radiotherapy and chemotherapy, radiotherapy alone, and chemotherapy alone.

Association of Blood Pressure, Blood Glucose, and Temperature With Neurological Outcome After Childhood Stroke

Abstract Full Text
JAMA Neurol. 2016;73(7):829-835. doi:10.1001/jamaneurol.2016.0992

This cohort study aims to determine the prevalence of abnormal blood pressure, blood glucose levels, and temperature in pediatric patients with acute arterial ischemic stroke and to explore any association between these measures and neurological outcome.

Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism

Abstract Full Text
JAMA Neurol. 2016;73(7):836-845. doi:10.1001/jamaneurol.2016.0363

This study uses whole-exome and targeted squencing to identify constitutional and mosaic mutations of MTOR associated with focal cortical dysplasia, hemimegalencephaly, and diffuse megalencephaly.

Neuropathologic Associations of Learning and Memory in Primary Progressive Aphasia

Abstract Full Text
JAMA Neurol. 2016;73(7):846-852. doi:10.1001/jamaneurol.2016.0880

This study of clinical and autopsy data examines the association of memory problems with primary progressive aphasia on the basis of autopsy-confirmed neuropathologic diagnoses of frontotemporal lobar degeneration vs Alzheimer disease.

Frequency of Synaptic Autoantibody Accompaniments and Neurological Manifestations of Thymoma

Abstract Full Text
JAMA Neurol. 2016;73(7):853-859. doi:10.1001/jamaneurol.2016.0603

This cross-sectional study reports the proportion of patients with thymoma who had potentially pathogenic neural synaptic autoantibodies.

The Association of Chemotherapy-Induced Peripheral Neuropathy Symptoms and the Risk of Falling

Abstract Full Text
JAMA Neurol. 2016;73(7):860-866. doi:10.1001/jamaneurol.2016.0383

This study explores the association between the symptoms of chemotherapy-induced peripheral neuropathy and the risk of falls for patients receiving neurotoxic chemotherapy.

Review

Genomics of Alzheimer DiseaseA Review

Abstract Full Text
JAMA Neurol. 2016;73(7):867-874. doi:10.1001/jamaneurol.2016.0301

This review presents findings on the genetic mutations associated with Alzheimer disease, polymorphisms increasing risk, and amyloid β protein–reducing therapies.

Zika Virus as an Emerging Global PathogenNeurological Complications of Zika Virus

Abstract Full Text
free access has active quiz
JAMA Neurol. 2016;73(7):875-879. doi:10.1001/jamaneurol.2016.0800

This review article discusses what is currently known about Zika virus, neuroimmunologic complications, and the impact on global human health.

Clinical Pathologic Conference

A Young Man With Progressive Vision and Hearing Loss

Abstract Full Text
JAMA Neurol. 2016;73(7):880-883. doi:10.1001/jamaneurol.2016.1336

This case report describes a man with a history of progressive bilateral hearing loss and an acute left homonymous hemianopsia.

Images in Neurology

Branched Retinal Artery Occlusions and Susac Syndrome

Abstract Full Text
JAMA Neurol. 2016;73(7):884-885. doi:10.1001/jamaneurol.2016.0121

This case report describes a woman in her early 40s who presented to the emergency department with multiple scotomas in both eyes and auditory changes in her left ear.

Spontaneous Cerebrospinal Fluid Leak With Venous Engorgement Mimicking a Contrast-Enhancing Cervical Mass

Abstract Full Text
JAMA Neurol. 2016;73(7):886-887. doi:10.1001/jamaneurol.2016.0277

This case report describes a woman in her early 40s with fluctuating neck pain in whom imaging revealed spontaneous cerebrospinal fluid leakage with engorgement of venous plexus.

Observation

Choreoathetosis, Dystonia, and Myoclonus in 3 Siblings With Autosomal Recessive Spinocerebellar Ataxia Type 16

Abstract Full Text
has multimedia
JAMA Neurol. 2016;73(7):888-890. doi:10.1001/jamaneurol.2016.0647

This case series describes members of the same family with spinocerebellar ataxia type 16 with choreoathetosis, dystonia, and myoclonus.

Comment & Response

Factors Affecting the Preventability of Stroke

Abstract Full Text
JAMA Neurol. 2016;73(7):890. doi:10.1001/jamaneurol.2016.1025

Factors Affecting the Preventability of Stroke—Reply

Abstract Full Text
JAMA Neurol. 2016;73(7):890-891. doi:10.1001/jamaneurol.2016.1028

Opsoclonus-Myoclonus Syndrome in the Era of Neuronal Cell Surface AntibodiesA Message for Clinicians

Abstract Full Text
JAMA Neurol. 2016;73(7):891. doi:10.1001/jamaneurol.2016.1161

Opsoclonus-Myoclonus Syndrome in the Era of Neuronal Cell Surface Antibodies—Reply

Abstract Full Text
JAMA Neurol. 2016;73(7):891. doi:10.1001/jamaneurol.2016.1164

Association Between Body Mass Index and Parkinson Disease

Abstract Full Text
JAMA Neurol. 2016;73(7):891-892. doi:10.1001/jamaneurol.2016.1242

Association Between Body Mass Index and Parkinson Disease—Reply

Abstract Full Text
JAMA Neurol. 2016;73(7):892. doi:10.1001/jamaneurol.2016.1245

Physiotherapy and Occupational Therapy and Mild to Moderate Parkinson Disease

Abstract Full Text
JAMA Neurol. 2016;73(7):892-893. doi:10.1001/jamaneurol.2016.1274

Physiotherapy and Occupational Therapy and Mild to Moderate Parkinson Disease

Abstract Full Text
JAMA Neurol. 2016;73(7):893-894. doi:10.1001/jamaneurol.2016.1277

Physiotherapy and Occupational Therapy and Mild to Moderate Parkinson Disease

Abstract Full Text
JAMA Neurol. 2016;73(7):894. doi:10.1001/jamaneurol.2016.1280

Physiotherapy and Occupational Therapy and Mild to Moderate Parkinson Disease—Reply

Abstract Full Text
JAMA Neurol. 2016;73(7):894-895. doi:10.1001/jamaneurol.2016.1283
Correction

Error in Figure Labeling

Abstract Full Text
free access
JAMA Neurol. 2016;73(7):895. doi:10.1001/jamaneurol.2016.2790
Book and Media Review

Review of Antiepileptic Drugs

Abstract Full Text
JAMA Neurol. 2016;73(7):896. doi:10.1001/jamaneurol.2016.1034
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2016;73(7):772. doi:10.1001/jamaneurol.2015.2468
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