This Viewpoint discusses medically assisted death in patients with brain injuries in whom functional magnetic resonance imaging that relies on blood oxygen levels in particular brain regions have been used to reveal signals that are interpreted as consciousness.
This cohort study examines the association between migraine and ischemic stroke due to cervical artery dissection in young patients with ischemic stroke.
This study identifies variations in the levels of antioxidant capacity and superoxide dismutase activity between adrenoleukodystrophy phenotypes in patients with cerebral adrenoleukodystrophy or adrenomyeloneuropathy, heterozygote female carriers, and healthy controls and correlates antioxidant levels with clinical outcome scores to determine a possible predictive value.
This study assesses the ability of neurofilament light chain to serve as a diagnostic biomarker in amyotrophic lateral sclerosis and the prognostic value of cerebrospinal fluid neurofilament light chain in patients with amyotrophic lateral sclerosis.
This study reports on the effect of depression on the risk of epilepsy and seizure outcomes.
This study evaluates neurofibrillary tangle burden in the presence of moderate or frequent plaques and its ability to predict clinical rate of Alzheimer diesase progression.
This study compares the functional independence at 3 months between patients treated for acute ischemic stroke under the drip-and-ship paradigm and those treated on site (mothership paradigm).
This case-control study compares patients with mild cognitive impairment, patients with AD dementia, and cognitively healthy patients to test whether plasma neurofilament light concentrations are increased in patients with AD and associated with cognitive decline, other AD biomarkers, and imaging evidence of neurodegeneration.
This study aims to determine if antioxidant supplements (vitamin E or selenium) used alone or in combination can prevent dementia in asymptomatic older men.
This case-control study assesses the association of melanopsin-mediated pupillary responses to blue and red light stimuli with abnormalities in retinal architecture in patients with multiple sclerosis.
This population-based case-control study examines the accumulation of amyloid in adults with childhood-onset epilepsy compared with a group of matched controls.
This case report describes a 72-year-old woman who presented with depression, an unexplained dry cough, and a sense of leg weakness and later developed memory and orientation problems, vertigo, and worsening parkinsonism.
A man in his 50s with an unremarkable medical history began experiencing vertigo 1 week after a viral upper respiratory tract infection.
A 21-year-old man had recurrent, transient episodes of dysarthria, dysphagia, and limb weakness over 3 days and later developed weakness and numbness of his limbs, with more severe symptoms on the right side. What is your diagnosis?
A 66-year-old woman with a history of a pituitary macroadenoma had intermittent diplopia of several years’ duration, iplopia was frequently present after repeatedly changing direction of gaze, and she noted mild right ptosis. What is your diagnosis?
A 58-year-old man presented with a 1-year history of severe and progressive action tremor in his dominant hand when writing. What is your diagnosis?
This case series describes 2 patients with Parkinson disease whose gonadal tissue specimens revealed aggregations of α-synuclein.