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Year

Day

December 5, 2016
Viewpoint

Progress in EpilepsyLatest Waves of Discovery

Abstract Full Text
JAMA Neurol. Published online December 5, 2016. doi:10.1001/jamaneurol.2016.2967

This Viewpoint discusses recent advances in the understanding of seizure disorders and future pathways of discovery for the treatment of epilepsy.

Editorial

Conformation-Specific Detection of α-SynucleinThe Search for a Biomarker in Parkinson Disease

Abstract Full Text
JAMA Neurol. Published online December 5, 2016. doi:10.1001/jamaneurol.2016.4813

Selective Serotonin Reuptake Inhibitors and Intracranial HemorrhageDeriving Clinical Relevance From an Epidemiologic Association

Abstract Full Text
JAMA Neurol. Published online December 5, 2016. doi:10.1001/jamaneurol.2016.5031
Original Investigation

Association of Selective Serotonin Reuptake Inhibitors With the Risk for Spontaneous Intracranial Hemorrhage

Abstract Full Text
JAMA Neurol. Published online December 5, 2016. doi:10.1001/jamaneurol.2016.4529

This population-based cohort study assesses the risk for intracranial hemorrhage associated with the use of selective serotonin reuptake inhibitors among new users of antidepressants and according to the strength of inhibition of serotonin reuptake.

Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid

Abstract Full Text
free access
JAMA Neurol. Published online December 5, 2016. doi:10.1001/jamaneurol.2016.4547

This study uses cerebrospinal fluid samples from patients with Parkinson disease to develop an assay for diagnosis of Parkinson disease.

JAMA Neurology Clinical Challenge

Cerebellar Ataxia and Hearing Impairment

Abstract Full Text
JAMA Neurol. Published online December 5, 2016. doi:10.1001/jamaneurol.2016.3426

A 51-year-old man presented with progressive difficulty walking and deciphering speech. One month later, he required a wheelchair, declined cognitively, and developed personality changes and seizures, eventually becoming completely mute. What is your diagnosis?

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