This Viewpoint discusses premature termination of spinal cord injury stem cell–based trials and advocates for clear termination guidelines including an orderly exit plan.
This worldwide patient registry study examines the most common features of glucose transporter type 1 deficiency.
This study characterizes the transcriptomics of peripheral monocytes in patients with amyotrophic lateral sclerosis.
This case report describes a 50-year-old man who presented with progressive clumsiness and unsteady gait and whose first symptoms began around age 39 years.
This randomized clinical trial assessed the feasibility of a home-based trial of melatonin vs placebo for adolescent migraine prevention.
This Viewpoint argues for enhanced seizure and epilepsy awareness and surveillance in infants with congenital ZIKV exposure.
This cohort study characterizes neurocognitive outcomes of boys with childhood cerebral adrenoleukodystrophy and early-stage cerebral disease who were treated with an allogeneic hematopoietic stem cell transplant and identifies disease- and treatment-related factors associated with long-term functioning.
This cohort study explores whether amyloid protective factors and Alzheimer disease–pattern neurodegeneration protective factors differ in elderly individuals with Alzheimer disease and identifies midlife risk factors associated with amyloid deposition.
This case series study examines the myopathy, lactic acidosis, and sideroblastic anemia associated with YARS2-related mitochondrial disease.
This analysis of data from the National Inpatient Sample examines whether stroke hospitalization rates have continued to increase and identifies the prevalence of associated stroke risk factors among younger adults aged 18 to 54 years.
This case-control study compares clinical and angiographic outcomes between monitored anesthesia care and general anesthesia in patients presenting with vertebrobasilar occlusion strokes.
This case series examines whether cases of benign epilepsy with centrotemporal spikes are present in the North American SUDEP (Sudden Unexpected Death in Epilepsy) Registry.
This population-based study evaluates the incidence of childhood-onset epilepsy in mothers who were overweight or obese during early pregnancy.
This cohort study examines the prognostic significance of C-reactive protein in amyotrophic lateral sclerosis.
This case report describes adolescent-onset intractable epilepsy associated with myoclonus and neurocognitive decline to dementia in a young man.
A 30-year-old man was referred with progressive quadriplegia that started from the right lower limb and gradually spread to the upper limb and contralateral side. Cerebrospinal fluid testing revealed pleocytosis, elevated protein concentration, and a decreased glucose level, and magnetic resonance imaging of the cervical spine revealed multiple intramedullary lesions. What is your diagnosis?