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From The JAMA Network
March 2016

Translational Childhood Cancer GenomicsThe Future Is Now

Author Affiliations
  • 1Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
  • 2Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
  • 3Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
  • 4Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada
  • 5The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada
JAMA Oncol. 2016;2(3):384-385. doi:10.1001/jamaoncol.2015.5076

The cancer genomics era has brought with it a tidal wave of great improvements in our understanding of childhood cancer. Novel recurrent somatic driver events1 have been uncovered and many cancers can now be classified into subgroups on the basis of their shared genomic alterations. These allow for better risk stratification and treatment of children whose tumors are histopathologically indistinguishable.2

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